桑芒芒
学科（专业）：药物分析学
研究方向：血栓的靶向性治疗
邮箱：sangmangmang@163.com
电话：19850853556
教育背景：
1. 2010.9-2014.6 皖西学院, 制药工程学, 工学学士
2. 2014.9-2017.6 天津中医药大学, 药物分析学, 医学硕士
3. 2017.9-2020.6 中国药科大学, 药物分析学, 理学博士
工作经历：
2020.8-至今 厦门大学附属心血管病医院（心研所） 副研究员
主要研究领域：
桑芒芒副研究员主要研究方向为采用纳米材料及免疫细胞追踪术对静脉血栓及动脉粥样硬化进行靶向性治疗。近年来在国际知名杂志发表论著10余篇；承担省市级科研项目2项。
主要学术成果：
论文：
1. Sang M, Luo R, Bai Y, et al. BHQ-Cyanine Based “Off-On” Long-Circulating Assembly as Ferroptosis Amplifier for Cancer Treatment: a Lipid-Peroxidation Burst Device[J]. ACS applied materials & interfaces, 2019. IF=8.758
2. Sang M, Luo R, Bai Y, et al. Mitochondrial membrane anchored photosensitive nano-device for lipid hydroperoxides burst and inducing ferroptosis to surmount therapy-resistant cancer[J]. Theranostics, 2019, 9(21): 6209. IF= 8.579
3. MM Sang, Fu Lei Liu, Yang Wang, et al. Wenyuan Liu and Feng Zheng. A novel redox/pH dual-responsive and hyaluronic acid-decorated multifunctional magnetic complex micelle for targeted gambogic acid delivery for the treatment of triple negative breast cancer. drug delivery.2018. IF= 6.402
4. Sang M, Zhang Z, Liu F, et al. Multifunctional hyaluronic acid-decorated redox-responsive magnetic complex micelle for targeted drug delivery with enhanced antitumor efficiency and anti-cell-migration activity[J]. Journal of biomedical nanotechnology, 2018, 14(3): 477-495. IF= 5.068
5. Sang M, Lingfei Han, Luo R et al. CD44 Targeted Redox-Triggered Self-assembly with Magnetic Enhanced EPR Effect for Efficacy Amplification of Gambogic Acid to Triple-Negative Breast Cancer. Biomaterials Science, 2019. IF= 6.183
6. Sang M, Du G, Hao J, et al. Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology. [J]. Journal of Pharmaceutical & Biomedical Analysis, 2017, 139:37-43. IF= 3.255
7. Jinrong Zheng, Yue Xu, Lixue Fan, Shuheng qin, Hua Li, Ruixi Li, Mangmang Sang, Haiyan Chen, Zhenwei Yuan, Bowen Li. A Bio-responsive Near-Infrared Fluorescent Probe for Facile and Persistent Live-Cell Tracking [J]. Small. 2020, DOI: 10.1002/smll.202002211.IF=11.4
8. Fulei Liu, Xiaoxian Huang, Lingfei Han, Mangmang Sang, et al. Improved Druggability of Gambogic Acid Using a Core-Shell Nanoparticle [J]. Biomaterials science, 2019. IF= 6.183
9. Wang, L., Sang, M., Liu, E., Banahene, P. O., Zhang, Y., & Wang, T., et al. (2017). Rapid profiling and pharmacokinetic studies of major compounds in crude extract from polygonum multiflorum by uhplc-q-tof-ms and uplc-ms/ms. Journal of Pharmaceutical & Biomedical Analysis, 140, 45. IF= 3.255
10. Chen, N. D., Chen, H., Li, J., Sang, M. M., Ding, S., & Yu, H. (2015). Discrimination and similarity evaluation of tissue-cultured and wild dendrobium, species using fourier transform infrared spectroscopy. Journal of Molecular Structure, 1086, 255-265.
11. Wang, L. L., Han, L. F., Yu, H. S., Sang, M. M., Liu, E. W., & Zhang, Y., et al. (2015). Analysis of the constituents in "zhu she yong xue shuan tong" by ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry combined with preparative high performance liquid chromatography. Molecules, 20(11), 20518-37.
科研项目：
1. 江苏省研究生科研与实践创新计划，项目号：KYCX18_0768，2017.2-2018.12，主持
2. 厦门市医疗卫生指导项目，项目号：3502Z20209144，2021.1-2023.12，主持
获奖情况：
1. 2018年5月获得“Aptar医药 三等奖学金”，
2. 2019年5月获得“Aptar医药 三等奖学金”，
3. 2019年获得“国家奖学金”
4. 2020年获得“威尔曼优秀博士学位论文”
